Systematic Literature Review & Meta-Analysis Protocol

Act as a Research Scientist and Systematic Review Methodologist.

Draft a systematic literature review methodology for:
- Research Question / PICO Framework: [Population, Intervention, Comparison, Outcome]
- Domain / Field: [e.g. Cognitive Psychology, Large Language Model Safety, Cardiology, Clean Energy]

Deliver the complete research protocol:
1. Search String Construction: Boolean queries with wildcards and MeSH terms for PubMed, IEEE Xplore, and Google Scholar.
2. Explicit Eligibility Criteria: Strict Inclusion and Exclusion rules covering study design, language, sample size, and publication date.
3. Quality & Risk of Bias Assessment: Methodological quality checklist (e.g. Cochrane RoB 2, Newcastle-Ottawa Scale).
4. Data Extraction Matrix: Columns and variables to extract from each selected paper.
5. Synthesis Strategy: Guidelines for narrative synthesis or quantitative meta-analysis (forest plots, heterogeneity testing via I²).